Important considerations when treating pulmonary hypertension

In term and near-term neonates with HRF…

Start INOMAX promptly upon confirmation of pulmonary hypertension to improve oxygenation4 and help avoid higher levels of supplemental oxygen.

Considerations for the detection and management of pulmonary hypertension

  • What are the clinical signs that a term or near-term neonate has pulmonary hypertension?
  • What is the goal of raising FiO2 to >60%?
  • What are the consequences of prolonged hyperoxia?

When is it appropriate to test for pulmonary hypertension?

  • It is important to diagnose pulmonary hypertension as soon as possible5,6
  • Early intervention and treatment of pulmonary hypertension can help to prevent severe hypoxia5,6

Which tests are available to detect pulmonary hypertension?

  • Pre- and post-ductal saturations—a difference of >5% indicates pulmonary hypertension7
  • Arterial oxygen saturation–more than 2 desaturations (SaO2 <85%) occurring within a 12-hour period7
  • Echocardiogram—can detect extrapulmonary shunting and rule out structural or congenital heart disease5
  • X-ray imaging—may reveal evidence of lung disease5,6

Early intervention with INOMAX may help to avoid higher levels of supplemental oxygen.